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This medication is used to take care of depression. It is also used with other therapies for the treating nighttime bed-wetting (enuresis) in kids. Using this medicine to take care of despair may boost your mood, sleep, appetite, and degree of energy and could help restore your fascination with daily living. Imipramine might help your child control nighttime bed-wetting.

Imipramine belongs to a class of medicines called antidepressants that are tricyclic. It works by restoring the balance of certain natural substances (neurotransmitters such as norepinephrine) in the brain. For bed-wetting, this medicine may work by blocking the effect of a specific substance that is naturalacetylcholine) on the bladder.

DIFFERENT USES: This section contains uses of this drug that are not listed in the approved professional labeling for the medication but that may be prescribed by your quality of life care pro. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.

This drug may also be used for the treating anxiety and panic disorders.

Just how to use Tofranil

Read the medicine Guide available from your pharmacist. Consult your doctor or pharmacist when you have any questions.

Take this medication by lips with or without food, usually 1-4 times daily or as directed by your doctor. You to take the entire dose once daily at bedtime if you have daytime drowsiness, your doctor may direct. Dosage is based on your condition that is medical and to therapy. In children, dosage may also be based on body weight. To reduce your risk of adverse effects, your doctor may start you at a dose that is low gradually raise your dosage.

When found in children for bed-wetting, imipramine must be taken one hour before bedtime. If your child usually wets the bed early in the night, the drug may be given earlier in separate doses (e.g., one dose in the afternoon and one dose at bedtime).

Follow your doctor's instructions carefully. Do not take more or less medication or take it more frequently than prescribed. Your condition shall maybe not improve any faster and your risk of side impacts will increase. Make use of this medicine regularly so that you can have the benefit that is most from it. To help you remember, use it at the time( that is same) each day.

This medication does not away work right. It may take up to 3 weeks if you are taking this medication for depression before you experience the full benefits.

It is crucial to continue using this medication regardless if you feel great. Usually do not instantly stop using this medication without consulting your doctor. Some conditions may become worse if the drug is abruptly stopped. Your dose may gradually need to be decreased.

When used for a long period in children for bed-wetting, this medicine may not are well and might require different dosing. Talk with the doctor if this medicine prevents working well.

Inform your doctor if your condition persists or worsens.

Unwanted Effects

Dry lips, blurred vision, headache, drowsiness, dizziness, constipation, sickness, vomiting, loss of appetite, diarrhea, stomach cramps, weight gain/loss, and increased sweating might occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your medical professional has prescribed this medicine because he or she has judged that the benefit to you is greater than the risk of adverse effects. Many people using this medication do not have side that is serious.

Tell your medical practitioner right away if any of these unlikely but serious adverse effects occur: mental/mood changes (e.g., confusion, depression, memory problems), enlarged/painful breasts, unusual breast milk production, irregular/painful menstrual periods, muscle stiffness, restlessness, tinnitus, sexual problems (e.g., decreased sexual ability, changes in desire), shakiness (tremors), numbness/tingling of the hands/feet, pain/redness/swelling of arms or feet, trouble urinating.

Inform your physician right away if any of those unusual but really serious adverse effects happen: effortless bruising/bleeding, signs of infection (e.g., fever, persistent sore throat), severe stomach/abdominal pain, dark urine, yellowing of eyes/skin.

This medication may increase serotonin and rarely cause an extremely serious condition called serotonin syndrome/toxicity. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take (see Drug Interactions section). Get medical help appropriate away if you develop some of the following symptoms: fast heartbeat, hallucinations, loss in coordination, serious dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, uncommon agitation/restlessness.

Get medical help right away when you have any very serious part impacts, including: chest discomfort, slow/fast/irregular heartbeat, fainting, seizures, slurred speech, weakness on one side of this human anatomy, attention pain/swelling/redness, vision changes (such as seeing rainbows around lights through the night).

A really severe reaction that is allergic this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious reaction that is allergic: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble respiration.

This is not a list that is complete of adverse effects. If you notice other effects not listed above, contact your pharmacist or doctor.

In america -

Call your medical professional for medical advice about unwanted effects. You may report adverse effects to Food And Drug Administration at 1-800-FDA-1088 or at

In Canada - Call your doctor for medical advice about side impacts. You'll report effects that are side Health Canada at 1-866-234-2345.


Before taking this medication, tell your doctor or pharmacist in the event that you have any other allergies if you are allergic to it; or to other tricyclic antidepressants (such as desipramine, amitriptyline); or. This product may contain inactive ingredients, which could cause allergy symptoms or other problems. Communicate with your pharmacist for lots more details.

This medication should not be used if you've got a certain condition that is medical. Before using this medicine, consult your doctor or pharmacist if you have had: a heart attack that is recent.

Before applying this medicine, tell your doctor or pharmacist your medical history, particularly of: difficulty in breathing (e.g., asthma, chronic bronchitis), individual or genealogy of glaucoma (angle-closure type), diabetes, eating disorders (e.g., bulimia), heart problems (e.g., arrhythmias, coronary artery disease), liver dilemmas, kidney problems, individual or genealogy and family history of other mental/mood conditions (e.g., manic depression, schizophrenia), seizures, overactive thyroid (hyperthyroidism), trouble urinating (e.g., due to enlarged prostate), any condition that may raise your risk of seizures (e.g., alcohol/sedative dependency, utilization of electroconvulsive treatment, mind injury/disease such as for example stroke), certain types of tumors (e.g., pheochromocytoma, neuroblastoma).

Imipramine may cause a condition which affects one's heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat along with other symptoms (such as serious dizziness, fainting) that require medical attention right away.

The risk of QT prolongation may be increased when you yourself have specific medical conditions or are taking other medications that may cause QT prolongation. Before utilizing imipramine, tell your doctor or pharmacist of all of the the drugs you take and if you have actually some of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation into the EKG), genealogy of certain heart related illnesses (QT prolongation in the EKG, unexpected cardiac death).

Low levels of potassium or magnesium into the bloodstream may also increase your risk of QT prolongation. This risk may increase if you have conditions such as severe sweating, diarrhea, or vomiting if you use certain drugs (such as diuretics/"water pills") or. Confer with your doctor about using imipramine safely.

Before having surgery, tell your dentist or doctor you are taking this medication.

This drug may make you dizzy or drowsy or cause vision that is blurred. Do not drive, use machinery, or do any activity that requires alertness or clear vision you can perform such activities safely until you are sure. Limit alcoholic beverages.

To decrease dizziness and lightheadedness, get up slowly when increasing from a seated or lying position.

This drug may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear clothing that is protective out-of-doors.

If you have diabetes, this drug may make it harder to control your blood sugar levels. Check your blood sugar regularly as directed by your doctor. Tell your doctor right away if you have symptoms such as increased thirst/urination, shakiness, unusual sweating, or hunger. Your medication that is anti-diabetic or might need to be adjusted.

Older adults may be much more responsive to the side-effects of this drug, especially dizziness (more likely when standing up), drowsiness, constipation, trouble urinating, mental/mood changes (such as confusion, agitation) and heart impacts such as QT prolongation (see above). Dizziness, drowsiness, and confusion can boost the risk of falling.

Care is recommended when utilizing this medication in children. (See also the Warning section.)

This medication must be utilized only when clearly needed during pregnancy. Infants born to mothers who have taken similar medicines during pregnancy may have signs such as trouble urinating, prolonged sleepiness, shaking, and seizures. Discuss the dangers and benefits with your physician.

Since untreated mental/mood issues (such as depression, anxiety, anxiety attacks) can be a condition that is serious do not stop taking this medication unless directed by your doctor. You may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy if you are planning pregnancy, become pregnant, or think.

This medication passes into breast milk and may have undesirable effects on a nursing infant. Consult your physician before breast-feeding.

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