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Uses

This combination medication can be used to take care of signs of Parkinson's disease or Parkinson-like symptoms (such as shakiness, stiffness, difficulty moving). Parkinson's disease is thought to be caused by too little of a substance that is naturally occurringdopamine) within the mind. Levodopa modifications into dopamine in mental performance, helping to control movement. Carbidopa prevents the breakdown of levodopa in the bloodstream so more levodopa can enter the mind. Carbidopa can also reduce some of levodopa's side effects such as vomiting and nausea.

How to use Sinemet

Take this medication by mouth with or without food as directed by the doctor, usually three or four times per day.

Taking this medicine with meals may help to decrease nausea. It is best to avoid a diet that is high-proteinit decreases the number of levodopa that the body takes in) during treatment, unless directed otherwise by the doctor. Separate your dosage of the medication by because many hours as possible from any iron supplements or products containing iron (such as multivitamins with minerals) you may take. Iron can reduce the amount of this medication absorbed by the body. Consult your pharmacist or doctor to get more details.

The dosage is situated on your condition that is medical and to treatment. To reduce your risk of side effects, your doctor may direct you to start this medication at a dose that is low gradually increase your dose. Follow your physician's guidelines very carefully. This combination medication comes in various strengths with different amounts of levodopa and carbidopa in each tablet. Be sure you have the strength that is correct of drugs. Your doctor might also prescribe carbidopa alone to be studied with this combination.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.

Some patients may experience a "wearing-off" (worsening of symptoms) before the dose that is next due. An "on-off" impact may also take place, in which sudden short periods of stiffness occur. If these effects occur, contact your medical professional for feasible dosage adjustments which could help to minimize this effect.

Do not stop taking this medication without consulting your medical professional. Some conditions could become worse whenever this medication is quickly reduced or suddenly stopped. Your dose may need to be gradually reduced. (See also unwanted effects section.)

Inform your physician should your condition does not enhance or if it worsens.

adverse Results

Dizziness, lightheadedness, nausea, vomiting, loss of appetite, difficulty sleeping, uncommon dreams, or headache may happen. If some of these effects persist or worsen, tell your doctor or pharmacist quickly.

This medication may cause saliva, urine, or sweat to turn a color that is dark. This impact is harmless, your clothes can be stained.

To cut back the possibility of dizziness and lightheadedness, get up slowly when increasing from a sitting or lying position.

Remember that your doctor has prescribed this medication she has judged that the benefit to you is greater than the risk of side effects because he or. Many people using this medication do not have adverse that is serious.

Some individuals taking this medication have fallen asleep unexpectedly throughout their usual activities that are dailysuch as talking on the phone, driving). In some full instances, rest occurred without any emotions of drowsiness upfront. This sleep impact may occur anytime during treatment with carbidopa/levodopa even in the event you used this medication for a time that is long. If you experience increased sleepiness or fall asleep during the day, do not drive or do other possibly dangerous activities until you have discussed this effect with your doctor. Your risk with this sleep impact is increased by utilizing alcohol or other medicines that may cause you to drowsy. See also Precautions section.

Inform your physician right away you can't control/spasms, greatly increased eye blinking/twitching, fainting, vision changes (such as blurred vision, double vision), eye pain, severe stomach/abdominal pain, black/tarry stools, vomit that looks like coffee grounds, mental/mood changes (such as agitation, hallucinations, depression, thoughts of suicide), signs of infection (such as sore throat that doesn't go away), easy bleeding/bruising, unusual tiredness, tingling of the hands/feet, unusual strong urges (such as increased gambling, increased sexual urges) if you have any serious side effects, including: new/worsening movements.

Get medical help right away if you have any very severe side results, including: upper body pain.

Suddenly stopping or reducing the dose of the medicine may seldom cause a tremendously serious condition called neuroleptic malignant syndrome (NMS). Get medical help straight away when you yourself have any of the after symptoms: temperature, unusual muscle mass stiffness, severe confusion, perspiring, fast/irregular heartbeat, rapid breathing.

an extremely serious allergic reaction to this drug is rare. However, get help that is medical away in the event that you notice any observeable symptoms of a serious sensitive reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble respiration.

This is not a list that is complete of side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the usa -

Call your doctor for medical advice about unwanted effects. You could report side effects to Food And Drug Administration at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your medical practitioner for medical advice about side impacts. You may report effects that are side Health Canada at 1-866-234-2345.

Precautions

Before using this medication, tell your doctor or pharmacist in the event that you are allergic to carbidopa or levodopa; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergies or other problems. Communicate with your pharmacist for more details.

Before making use of this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, glaucoma, breathing issues (such as asthma), heart disease (such as for instance coronary attack, irregular heartbeat), kidney infection, stomach/intestinal ulcer, mental/mood disorders (such as for instance depression, schizophrenia), blood disorders, seizures, sleep disorders.

This drug might make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness you can perform such activities safely until you are sure. Limit beverages that are alcoholic. See also Side Results part.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

During pregnancy, this medication should be utilized only once obviously needed. Discuss the risks and benefits with your medical professional.

Levodopa passes into breast milk. Its unknown if carbidopa passes into breast milk. Consult with your doctor before breast-feeding.


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