Methotrexate can be used to treat certain forms of cancer tumors or to control psoriasis that is severe rheumatoid arthritis that has not responded to other treatments. It may also be used to control rheumatoid arthritis that is juvenile. Methotrexate belongs to a class of drugs known as antimetabolites. It works by slowing or stopping the growth of cancer cells and suppressing the system that is immune.
Early remedy for arthritis rheumatoid with more aggressive therapy such as for example methotrexate helps to reduce further joint damage and to preserve function that is joint.
OTHER USES: This section contains uses of this medication which can be not listed in the approved professional labeling for the drug but which could be prescribed by your health care professional. Use this drug for a state of being which is placed in this area as long as it offers been therefore prescribed by your medical care professional.
This medication may also be used for lupus and psoriatic arthritis.
Read the Patient Information Leaflet if available from your pharmacist you get a refill before you start taking methotrexate and each time. If you have any relevant questions, pose a question to your doctor or pharmacist.
Methotrexate is a strong medication. The dosage and how often you take this medication are based on your medical condition and response to therapy. There are many dosing that is different for this medication (especially for cancer therapy). Therefore, it is vital that you follow your doctor's guidelines carefully. Take this medication by mouth as directed by your doctor.
For the treating psoriasis or rheumatoid arthritis, just take this medication by mouth as directed by your physician, frequently once a week. It may take around a few months before you get the benefit that is full of drug.
Never increase your dose or use this drug more often or for longer than prescribed. Your condition shall not improve any faster, and your risk of side-effects will increase.
Since this drug can be consumed through skin and lung area that can harm an unborn baby, women who are pregnant or who may get pregnant should not handle this medication or breathe the dirt from the tablets.
Drink plenty of liquids while taking this medication unless your doctor informs you otherwise. Doing so helps your kidneys to get rid of the medication from the body and prevent a few of the relative negative effects.
See also Warning section.
Sickness, vomiting, stomach pain, drowsiness, or dizziness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist quickly.
Short-term hair loss might occur. Normal hair regrowth should return after treatment has ended.
Remember that your particular physician has recommended this medication she has judged that the benefit to you is greater than the risk of side effects because he or. Many people using this medication do not have serious adverse effects.
Tell your doctor appropriate away in the event that you have any adverse that is serious, including: mouth sores, diarrhea, signs of anemia (such as for instance unusual tiredness, pale skin), signs of liver issues (such as for instance dark urine, persistent nausea/vomiting, stomach/abdominal pain, yellowing eyes/skin), easy bruising/bleeding, black stools, enlarged glands/lymph nodes, bone tissue pain, unusual pain and discoloration of your skin, modification in the quantity of urine, dry cough, muscle weakness.
Get medical help right away if you have any very serious unwanted effects, including: weakness on one side regarding the body, neck stiffness, severe headache, vision changes, irregular heartbeat, mental/mood changes, seizures.
This medication may lower your ability to fight infections. This may make you more likely to get a serious (rarely fatal) infection or make any infection you have worse. Tell your doctor right away if you have any signs of infection (such as fever, chills, persistent sore throat, coughing).
This medication can affect sperm production, a result that may lower fertility that is male. Check with your doctor for more details.
A very severe allergic reaction to this drug is rare. However, get help that is medical away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially associated with face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your pharmacist or doctor.
Into the US -
Phone your physician for medical advice about side-effects. You might report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about negative effects. You may report side effects to wellness Canada at 1-866-234-2345.
See also Warning section.
Before taking methotrexate, inform your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other issues. Talk to your pharmacist for more details.
Before by using this medication, tell your doctor or pharmacist your medical background, especially of: liver illness, kidney infection, lung disease (such as pulmonary fibrosis), liquor use, suppressed immunity system, blood cell/bone marrow disorders, stomach/intestinal diseases (such as peptic ulcer, ulcerative colitis), any active disease (including chickenpox or present exposure to it), folic acid deficiency.
Methotrexate makes you more likely to get infections or may worsen any current infections. Therefore, clean your hands well to avoid the spread of infection. Avoid contact with individuals who have infections that may spread to other people (such as chickenpox, measles, flu). Consult your doctor when you have been subjected to an infection or for more details.
Don't have immunizations/vaccinations without the consent of your doctor. Prevent connection with those that have recently received live vaccines (such as flu vaccine inhaled through the nose).
To lower the possibility of getting cut, bruised, or injured, use caution with razor-sharp objects like razors and nail cutters, and avoid activities such as for example contact sports.
This drug might make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.
Before having surgery, tell your medical professional or dental practitioner about all the products you utilize (including prescription drugs, nonprescription drugs, and herbal products).
This medicine may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors.
Methotrexate must not be utilized during maternity. It might harm an unborn baby. It is important to prevent pregnancy during and after treatment with methotrexate. Therefore, males and females must use reliable forms of birth control (such as condoms, birth control pills) during treatment. Males should continue to use birth control for at least 3 months after the final end of treatment. Females should continue to use birth control for at minimum 1 cycle that is menstrual the end of treatment. You may be pregnant, tell your doctor right away if you become pregnant or think.
Because this drug can be absorbed through the epidermis and lungs and may harm an baby that is unborn women that are pregnant or who may get pregnant should not handle this medicine or breathe the dust from the tablets.
Methotrexate passes into breast milk and may harm a medical infant. Therefore, breast-feeding while using the this drug isn't recommended. Check with your physician before breast-feeding.
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