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Duloxetine is employed to treat depression and anxiety. In addition, duloxetine is employed to simply help relieve neurological pain (peripheral neuropathy) in people with diabetes or ongoing pain due to health conditions such as for instance arthritis, chronic back discomfort, or fibromyalgia (a state of being which causes widespread pain).

Duloxetine may improve your mood, sleep, appetite, and degree of energy, and decrease nervousness. It can also decrease pain as a result of specific medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the mind.

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OTHER USES: This part contains uses of this drug which can be not listed in the approved professional labeling for the drug but which could be prescribed by your health care pro. Use this drug for a disorder that is listed in this section only if it was so prescribed by your wellbeing care professional.

This medicine doubles to help treat other painful nerve conditions (neuropathic pain).

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Read the Medication Guide and, if available, the Patient Information Leaflet given by your pharmacist you get a refill before you start using duloxetine and each time. If you have any relevant questions, ask your doctor or pharmacist.

Take this medication by mouth as directed by your doctor, frequently 1 or 2 times a with or without food day. If you have nausea, it may help to take this drug with food. Swallow the capsule whole. Do not crush or chew the capsule or mix the contents with food or liquid. Doing so can launch all the drug at once, increasing the risk of side effects.

The dosage is dependant on your age, medical condition and response to treatment. To reduce your risk of side effects, your doctor may direct one to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. Take this medication regularly to get the benefit that is most from this. To simply help you remember, just take it at the same time(s) each day.

You will need to continue taking this medicine as prescribed even in the event that you feel well. Do not stop taking this medication without consulting your physician. Some conditions could become worse when this drug is abruptly stopped. Also, you may experience symptoms such as dizziness, confusion, mood swings, headache, tiredness, diarrhoea, rest changes, and brief feelings similar to electric shock. Your dose may gradually need to be decreased to reduce adverse effects. Report any brand new or symptoms that are worsening away.

Inform your physician when your condition persists or worsens.

Part Effects

See also Warning section.

Nausea, dry lips, constipation, loss of appetite, tiredness, drowsiness, or increased sweating may occur. If some of these effects persist or worsen, tell your doctor promptly.

Dizziness or lightheadedness might occur, particularly when you first start or increase your dose of this drug. To reduce the risk of dizziness, lightheadedness, or falling, get up slowly when rising from a sitting or lying position.

Remember that your doctor has prescribed this medication she has judged that the benefit to you is greater than the risk of side effects because he or. Many people using this medication do not have side that is serious.

This medicine may raise your blood pressure. Check your blood pressure regularly and tell your doctor if the total results are high.

Tell your doctor right away if any one of these serious side impacts occur: confusion, easy bruising/bleeding, decreased interest in sex, changes in intimate ability, muscle tissue cramps/weakness, shaking (tremor), difficulty urinating, unusual decrease in the amount of urine, signs of liver problems (such as stomach/abdominal pain, persistent sickness, vomiting, yellowing eyes/skin, dark urine).

Get medical help straight away if you have got any very severe side effects, including: black/bloody stools, vomit that appears like coffee grounds, seizure, eye pain/swelling/redness, vision changes (such as for example seeing rainbows around lights at night, blurred vision).

This medication may increase serotonin and rarely cause a tremendously serious condition called serotonin syndrome/toxicity. The risk increases you take (see Drug Interactions section) if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs. Get medical help right away if you develop some of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, serious nausea/vomiting/diarrhea, twitching muscles, unexplained fever, uncommon agitation/restlessness.

an extremely serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a critical allergic effect, including: rash, itching/swelling (especially of the face/tongue/throat), serious dizziness, trouble breathing, skin blisters, mouth sores.

That is not a complete list of possible adverse effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at

In Canada - Call your doctor for medical advice about side effects. You might report effects that are side wellness Canada at 1-866-234-2345.


Before using duloxetine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain ingredients that are inactive that may cause allergic reactions or other dilemmas. Talk to your pharmacist to get more details.

Before using this medication, inform your doctor or pharmacist your medical history, especially of: personal or family history of psychiatric disorders (such as for instance bipolar/manic-depressive disorder), personal or family history of suicide attempts, bleeding dilemmas, personal or household history of glaucoma (angle-closure type), raised blood pressure, kidney disease, liver disease, seizure disorder, stomach issues (such as slow emptying regarding the stomach), use/abuse of alcohol.

This medication may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness you can perform such activities safely until you are sure. Avoid alcoholic beverages.

If you have diabetes, duloxetine may affect your blood sugar levels. Always check your glucose levels frequently as directed by the doctor. Your doctor may require to regulate your diabetes medication, workout program, or diet.

Before having surgery, tell your doctor or dentist about all of the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Older adults may be more responsive to the relative side effects of this drug, especially bleeding, dizziness, lightheadedness, or loss of coordination. Older adults may be more likely also to develop a form of salt imbalance (hyponatremia), particularly if they are taking "water pills" (diuretics). Dizziness, lightheadedness, or loss of coordination can boost the danger of falling.

Children may be more painful and sensitive to the relative side effects of this drug, especially loss of appetite and weight loss. Monitor height and weight in children that are taking this drug. See also Warning.

During pregnancy, this medicine should really be used only when clearly needed. It may harm an unborn baby. Also, babies born to mothers who have used this drug during the last 3 months of pregnancy may develop withdrawal symptoms rarely such as feeding/breathing difficulties, seizures, muscle tightness, or constant crying. In the event that you notice some of these symptoms in your newborn, promptly tell the doctor.

Since untreated mental/mood problems (such as depression, anxiety) is a condition that is serious do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss the benefits and risks of using this medication during pregnancy with your doctor.

This medication passes into breast milk and could have undesirable effects on a nursing infant. Consult with your doctor before breast-feeding.

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