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This medicine can be used to prevent or treat gout assaults (flares). Usually gout symptoms develop instantly and involve only one or a few joints. The big toe, knee, or ankle joints are frequently affected. Gout is caused by too much acid that is uric the blood. When acid that is uric within the blood are way too high, the uric acid may form hard crystals in your joints. Colchicine works by decreasing swelling and lessening the create up of the crystals crystals that hurt within the affected joint(s).

This medication is also used to avoid attacks of pain into the abdomen, chest, or joints caused by a certain inherited disease (familial Mediterranean fever). It really is thought to the office by decreasing the body's production of a protein that is certain A) that builds up in people with familial Mediterranean fever.

Colchicine is not a discomfort medication and really should perhaps not be used to alleviate other factors behind discomfort.

DIFFERENT USES: This area contains uses of this drug which are not detailed in the approved labeling that is professional the drug but which may be prescribed by your health care professional. Use this medication for a condition that is detailed in this area only if it was therefore recommended by your health care professional.

This medication may be used to also reduce swelling and inflammation associated with sac that covers the surface of the heart, an ailment called pericarditis.

How to use colchicine

Read the Medication Guide supplied by your pharmacist you get a refill before you start taking colchicine and each time. If you have any relevant questions concerning the information, ask your medical practitioner or pharmacist.

Take this medication by mouth with or without meals, precisely as directed by your physician. Dosing recommendations vary widely and may be different from the recommendations that are following. Taking more than the recommended dose may maybe not increase this drug's effectiveness and may increase your risk for adverse effects. Ask your doctor or pharmacist to get more details.

If you are taking this medicine to treat a gout attack, follow the directions carefully given by your doctor. This medication works best at the first sign of an attack if you take it. The recommended dose is 1.2 milligrams at the sign that is first of attack, followed by 0.6 milligrams one hour later. The maximum recommended dose is 1.8 milligrams taken over a 1-hour period. Ask your physician ahead of time about how soon you can repeat treatment using this medication if you have another gout attack.

If you are taking this medication to prevent gout attacks or for pericarditis, ask your doctor about the dose and schedule you should follow. Very carefully follow your doctor's directions.

If you are taking this medication to prevent attacks of pain caused by familial Mediterranean fever, the usual dose is 1.2 to 2.4 milligrams daily. The dose that is total be taken once daily or divided into two doses a day. Your medical professional might have to adjust your dose to control your symptoms or when you yourself have unwanted effects.

The dosage is founded on your medical condition, other drugs/foods you may be taking, and response to treatment. To reduce your risk for serious adverse effects, do not increase your dose, frequently take it more, and take it for a longer time than directed by the medical practitioner. Serious side effects may take place even at typical doses that are prescribed.

When your medical practitioner directs you to take colchicine regularly, use it frequently to get the benefit that is most from it. To help you remember, take it at the same time(s) each day.

Avoid eating grapefruit or drinking grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of certain medications in your bloodstream. Consult your pharmacist or doctor for more details.

If it worsens if you are taking this medication to treat symptoms due to familial Mediterranean fever, tell your doctor if your condition does not improve or.

What conditions does colchicine treat?

Side Effects

Diarrhea, nausea, cramping, abdominal pain, and vomiting may occur. If any of these effects persist or aggravate, tell your pharmacist or doctor promptly.

Understand that your medical professional has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious adverse effects.

Stop using this medication and get help that is medical away if any of these really serious side-effects occur: unusual bleeding/bruising, serious diarrhoea or vomiting, muscle tissue weakness or pain, numbness/tingling in your fingers or toes, pale or grey color regarding the lips/tongue/palms of hands, indications of infection (such as for instance temperature, persistent sore neck), unusual weakness/tiredness, fast heartbeat, shortness of breath, change in the total amount of urine.

An extremely serious reaction that is allergic this drug is rare. However, seek immediate attention that is medical you observe any symptoms of a critical hypersensitive reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble respiration.

This just isn't a list that is complete of side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the usa -

Phone your doctor for medical advice about adverse effects. You may possibly report effects that are side FDA at 1-800-FDA-1088 or at

In Canada - Phone your physician for medical advice about side impacts. You'll report effects that are side Health Canada at 1-866-234-2345.

Record adverse that is colchicine by likelihood and severity.


Before using this medicine, tell your medical professional or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic responses or other problems. Speak with your pharmacist for additional information.

Before using this medication, tell your medical professional or pharmacist your history that is medical of: renal problems, liver dilemmas (such as cirrhosis).

Liquor can decrease this drug's effectiveness. Limit liquor while using this drug.

This medication can influence how well your body absorbs some foods and nutritional elements (such as vitamin B12). Consult with your doctor or pharmacist for more details.

Before having surgery, tell your doctor or dental practitioner about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Older adults may be more sensitive to the relative side-effects of this medication, especially muscle tissue weakness/pain and numbness/tingling within their fingers or feet.

Colchicine can decrease production that is sperm which may affect the capability of a male to father a kid. Consult your doctor for more information.

During maternity, this medication should be properly used only if clearly needed. Discuss the potential risks and benefits along with your doctor.

This medication passes into breast milk. While there were no reports of harm to nursing infants, consult your doctor before breast-feeding. Your doctor may suggest that you separate the time(s) you take your medication apart from breast-feeding.

What should I know regarding pregnancy, nursing and administering colchicine to young ones or the elderly?

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