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Clomipramine is used to treat obsessive compulsive disorder (OCD). It helps decrease persistent/unwanted thoughts (obsessions), and it helps reduce the urge to perform repeated tasks (compulsions such as hand-washing, counting, checking) that interfere with everyday living.

This medication belongs to a class of medications called antidepressants that are tricyclic. It works by restoring the balance of certain natural substances (serotonin, among others) in the mind.

DIFFERENT USES: This section contains uses of this medication which are not listed in the approved professional labeling for the drug but which may be prescribed by your medical care professional. Make use of this drug for a condition that is listed in this area only if it is often so prescribed by your health care professional.

This medication has additionally been used to treat depression, panic assaults, and ongoing pain.

How exactly to make use of Anafranil

Read the Medication Guide available from your own pharmacist. Check with your pharmacist or doctor if you have any concerns.

Take this medication by mouth with or without food as directed by your medical professional. To minimize unwanted effects such as stomach upset, clomipramine may be started at a dose that is low given in several doses during the day with meals, and slowly increased as your body gets used to it. For you, the total dose can be taken once daily, usually at bedtime to prevent daytime drowsiness or as directed by your doctor after you have reached the best dose. Frequently, the daily dose will maybe not be more than 250 milligrams for adults and 200 milligrams for kids and teenagers.

Follow your medical practitioner's directions carefully. Do not take more or less medication or take it more frequently than prescribed. Your condition will not improve any faster and your risk of adverse effects such as for example seizures may be increased. Dosage is founded on your medical condition and response to therapy.

Avoid eating drinking or grapefruit grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of certain medications in your bloodstream. Consult your doctor or pharmacist for additional information.

Use this medication regularly in order to have the most benefit from it. Continue to take it even if you feel well. To help you remember, use it at the time( that is same) each time.

Do not suddenly stop using this medication without consulting your medical professional. Some conditions may become even worse when the drug is abruptly stopped. You could experience sweating, dizziness, nausea, vomiting, headache, or irritability if you abruptly stop taking this drug. Your dose may gradually need to be decreased.

It may just take 2 to 3 days or longer ahead of the full ramifications of this medication are noticed. Inform your doctor if the condition persists or if it worsens.

adverse Effects

See also Warning section.

Dizziness, drowsiness, dry lips, constipation, stomach upset, nausea, vomiting, changes in appetite/weight, flushing, sweating, tiredness and blurred vision may occur. Anxiety symptoms may temporarily aggravate when you initially start taking clomipramine. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

To relieve mouth that is dry suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water or utilize a saliva substitute.

To prevent constipation, maintain a diet adequate in dietary fiber, drink plenty of water, and exercise. If you then become constipated while applying this drug, consult with your pharmacist for assist in selecting a laxative (age.g., stimulant-type with stool softener).

Understand that your doctor has recommended this medication she has judged that the benefit to you is greater than the risk of side effects because he or. Many people using this medication do not have adverse that is serious.

Tell your physician right away if some of these unlikely but serious adverse effects happen: mental/mood changes (e.g., confusion, depression, memory problems), enlarged/painful breasts, unwanted breast milk production, irregular/painful menstrual durations, muscle stiffness, ringing in the ears, sexual dilemmas (e.g., decreased sexual ability, alterations in desire), shakiness (tremors), numbness/tingling associated with hands/feet, difficulty urinating.

Tell your physician straight away if any of these rare but very adverse that is serious occur: easy bruising/bleeding, signs of infection (e.g., fever, persistent sore throat), unusual/uncontrolled movements (especially associated with the tongue/face/lips), severe stomach/abdominal pain, dark urine, yellowing of eyes/skin.

This medication may increase serotonin and seldom cause a very serious condition called serotonin syndrome/toxicity. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take. Get medical help right away in the event that you develop some of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscle tissue, unexplained fever, unusual agitation/restlessness.

Get help that is medical away if you have any very severe side effects, including: black stools, chest pain, fainting, slow/fast/irregular heartbeat, seizures, vomit that looks like coffee grounds, eye pain/swelling/redness, vision modifications (such as seeing rainbows around lights during the night).

An extremely serious reaction that is allergic this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially associated with face/tongue/throat), severe dizziness, trouble breathing.

It is not a complete list of possible adverse effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Phone your doctor for medical advice about adverse effects. You may report effects that are side FDA at 1-800-FDA-1088 or at

In Canada - Call your doctor for medical advice about negative effects. You might report effects that are side Health Canada at 1-866-234-2345.


Before taking clomipramine, tell your doctor or pharmacist if you are allergic to it; or to other tricyclic antidepressants (e.g., imipramine, nortriptyline); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergies or other problems. Confer with your pharmacist for more details.

Before making use of this medication, tell your doctor or pharmacist your medical background, especially of: bloodstream dilemmas (age.g., purpura, thrombocytopenia), breathing problems (age.g., asthma, chronic bronchitis), personal or genealogy and family history of glaucoma (angle-closure type), eating disorders (age.g., bulimia), heart dilemmas (e.g., arrhythmias, coronary artery disease, recent heart attack), intestinal dilemmas (e.g., chronic constipation, ileus), liver problems, renal issues, personal or family history of other mental/mood conditions (e.g., bipolar disorder, schizophrenia), history of hospitalization for a very serious response to particular medicines (neuroleptic malignant problem), heartburn/stomach acid into the esophagus (e.g., due to hiatal hernia), seizures, overactive thyroid (hyperthyroidism), trouble urinating (urinary retention, enlarged prostate), any condition that may boost your risk of seizures (e.g., alcohol/sedative dependency, usage of electroconvulsive treatment, brain injury/disease), specific kinds of tumors (e.g., pheochromocytoma, neuroblastoma).

Clomipramine may cause an ailment that affects the heart rhythm (QT prolongation). QT prolongation can hardly ever cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that require medical attention straight away.

The danger of QT prolongation could be increased in the event that you have certain medical conditions or are using other drugs that could cause QT prolongation. Before using clomipramine, tell your physician or pharmacist of all the drugs you take if you have got any one of the following conditions: certain heart disease (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).

Lower levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you have conditions such as severe sweating, diarrhea, or vomiting if you use certain drugs (such as diuretics/"water pills") or. Talk to your medical practitioner about utilizing clomipramine safely.

This drug can make you dizzy or drowsy or cause temporary vision that is blurred. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages.

To decrease dizziness and lightheadedness, get up slowly when increasing from a seated or lying position.

Before having surgery, tell your dentist or doctor that you are taking this medication.

Caution is recommended when utilizing this medication in kids who be involved in active recreations since it might increase the possibility of heart problems. (See also the Warning section.)

Older adults may be more delicate to the relative unwanted effects of this medication, especially bleeding, confusion, dizziness, and QT prolongation (see above).

This medication should be used only when plainly needed during pregnancy. Newborns exposed to clomipramine during pregnancy might experience withdrawal symptoms or side-effects. Inform your doctor immediately in the event that you notice jitteriness, shaking, feeding problems, fast breathing, or seizures in your newborn.

Since untreated mental/mood dilemmas (such as for instance obsessive disorder that is compulsive depression, panic attack) can be a serious condition, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy.

This medication passes into breast milk and may have effects that are undesirable a nursing infant. Check with your doctor before breast-feeding.

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