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Pioglitazone is an anti-diabetic drug (thiazolidinedione-type, also called "glitazones") used along with a proper diet and exercise program to control high blood sugar in patients with diabetes. It really works by helping restore your body's proper reaction to insulin, thereby reducing your blood sugar.

Controlling blood that is high helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may lessen your risk also of a heart attack or stroke.

Pioglitazone is used either alone or in conjunction with other medications that are anti-diabeticsuch as for instance metformin or a sulfonylurea such as glyburide).

Speak to your physician about the potential risks and great things about pioglitazone.

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Read the Medication Guide provided by your pharmacist you get a refill before you start using pioglitazone and each time. If you have any relevant questions, ask your medical practitioner or pharmacist.

Take this medicine by mouth with or without food as directed by your medical professional, often once daily. Dosage is founded on your medical condition, response to treatment, and if you are taking other anti-diabetic drugs. Your doctor will adjust your dose based on your blood sugar levels to find the dose that is best for you. Follow your physician's directions carefully.

Take this medication frequently to be able to have the most benefit from it. Remember to use it at the same time each day.

If you are already using another drug that is anti-diabeticsuch as metformin or a sulfonylurea), follow your medical professional's directions very carefully for stopping/continuing the old medication and beginning this medication. Carefully stick to the medication treatment plan, meal plan, and workout program your doctor has suggested.

Check always your blood sugar levels regularly as directed by the doctor. Keep monitoring of the total results, and share them with your doctor. Tell your doctor if your blood sugar measurements are too high or too low. Your dosage/treatment might have to be changed. It could take as much as two to three months ahead of the full benefit of this drug takes effect.

Side Impacts

See also Warning section.

Sore neck, muscle tissue pain, weight gain, or tooth problems may possibly occur. If any of these effects persist or worsen, notify your pharmacist or doctor promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of adverse effects. Many people using this medication do not have serious side effects.

Inform your doctor appropriate away for those who have any side that is serious, including: new/worsening vision problems (such as blurred eyesight), bone fracture, reddish-colored urine, urgent need certainly to urinate, discomfort while urinating.

Pioglitazone might seldom cause liver disease. Inform your doctor immediately if you develop symptoms of liver infection, including: dark urine, yellowing of eyes/skin, persistent nausea/vomiting, stomach/abdominal pain.

Pioglitazone will not usually cause blood that is low (hypoglycemia). Low blood sugar may occur if this drug is prescribed with other medications that are anti-diabeticsuch as insulin or a sulfonylurea). Minimal blood sugar is more likely in the event that you drink large amounts of alcohol, do unusually heavy exercise, or do not consume enough calories from food. To help prevent blood that is low, consume dishes on a regular schedule, and do not skip meals. Consult with your pharmacist or doctor to uncover what you should do in the event that you miss a meal.

Outward indications of low blood sugar consist of unexpected sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or hands/feet that is tingling. It is a good habit to carry glucose tablets or gel to treat blood sugar that is low. If you don't have these dependable types of glucose, rapidly raise your blood sugar by eating a quick source of sugar such as for example dining table sugar, honey, or candy, or drink fruit juice or non-diet soda. Tell your medical practitioner right away about the response and the usage of this item.

Symptoms of high blood sugar (hyperglycemia) consist of thirst, increased urination, confusion, drowsiness, flushing, rapid respiration, or fruity breath odor. If these symptoms happen, tell your medical practitioner right away. Your dosage might need to be increased.

a really severe allergic reaction to this drug is rare. However, get medical help right away if you observe any of the after symptoms of a critical allergic reaction: rash, itching/swelling (especially of this face/tongue/throat), dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your pharmacist or doctor.

Into the US -

Call your medical practitioner for medical advice about part effects. You may report effects that are side FDA at 1-800-FDA-1088 or at

In Canada - Call your physician for medical advice about side impacts. You might report side effects to Health Canada at 1-866-234-2345.


Before taking pioglitazone, tell your doctor or pharmacist in the event that you are allergic to it; or if you have any other allergies. This product may contain ingredients that are inactive which can cause allergic reactions or other problems. Speak to your pharmacist to get more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart disease (such as congestive heart failure, chest pain), liver disease, fluid in your lungs, swelling (edema), anemia, a certain eye problem (macular edema), bladder cancer.

You might experience blurred vision, dizziness, or drowsiness due to extremely low or blood that is high levels. Do not drive, use machinery, or do any activity that requires alertness or clear vision you can perform such activities safely until you are sure.

Limit alcohol while taking this medication as it can increase the risk of developing blood sugar that is low.

It might be harder to control your blood sugar when your body is stressed (such as due to fever, infection, injury, or surgery). Consult your doctor because increased stress may require a noticeable change in your treatment plan, medications, or blood sugar levels testing.

Before having surgery, tell your medical practitioner or dentist about all the services and products you use (including prescription drugs, nonprescription drugs, and herbal services and products).

Pioglitazone may boost the risk of bone fracture in ladies (usually into the upper arm, hand, or base). See also Notes part.

Pioglitazone can cause changes into the cycle that is menstrualpromote ovulation) and increase the risk of becoming pregnant. Consult your pharmacist or doctor about the employment of trustworthy birth control when using this medication.

This medication ought to be used only if obviously required during pregnancy. Discuss the risks and advantages with your physician. Your medical practitioner may substitute insulin for this drug throughout your pregnancy. Follow all instructions carefully.

It's not known whether this drug passes into breast milk. Consult with your doctor before breast-feeding.

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