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This medication is utilized to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum may lead to acne that is severe. If left untreated, severe acne may cause permanent scarring.

OTHER USES: This section contains uses of this drug which are not detailed in the approved professional labeling for the drug but which could be prescribed by your health care expert. Use this drug for a condition which is placed in this section only if it has been so prescribed by your wellness care professional.

This medicine are often used to deal with a certain type of cancer (neuroblastoma).

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Read the Medication Guide given by your pharmacist you get a refill before you start using isotretinoin and each time. Read and sign a Patient Information/Informed Consent form before you start taking this medication. If you have any relevant questions regarding isotretinoin, consult your medical practitioner or pharmacist before taking the medication.

Swallow capsules whole. Don't crush or chew them. Isotretinoin is often taken twice daily for 15-20 weeks, or as directed by your physician. Directions for many generic forms of isotretinoin state that it should really be taken with dishes. However, the FDA has indicated that the Absorica brand name might be taken with or without food. Food helps increase absorption of this drug into your bloodstream. Ask your doctor or pharmacist for lots more information. Take this drug with a glass that is full of, and do not lie down for 10 moments after taking it.

The dosage is founded on your medical condition, weight, and reaction to treatment.

Your acne may worsen throughout the very first day or two of using this drug, plus it may occupy to 1-2 months before you spot the benefit that is full of medication. If severe acne returns, a second course of treatment may be started after you have stopped taking the drug for 2 months. The manufacturer doesn't recommend long-term use of isotretinoin. Don't take more than the recommended dose.

Since this drug is absorbed through the skin and lung area and may damage an baby that is unborn ladies who are pregnant or who can become pregnant should not manage this medicine or breathe the dust from the capsules.

Side Effects

Dry lips and mouth, minor swelling of the eyelids or lips, crusty epidermis, nosebleeds, upset belly, or thinning of locks may occur. If some of these effects persist or aggravate, tell your doctor or pharmacist immediately.

To relieve dry mouth, suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or make use of a saliva substitute.

Keep in mind that your physician has recommended this medication because he or she has judged that the benefit to you is greater than the risk of adverse effects. Many people using this medication do not have side that is serious.

Tell your physician right away in the event that you have actually any of these unlikely but serious side effects: mental/mood changes (e.g., depression, aggressive or violent behavior, and in rare situations, thoughts of suicide), tingling feeling in your skin, quick/severe sunburn (sun sensitiveness), back/joint/muscle pain, signs of illness (e.g., fever, persistent sore throat), painful swallowing, peeling skin on palms/soles.

Isotretinoin may seldom cause disease of this pancreas (pancreatitis) that may rarely be deadly. Stop taking this medication and inform your physician right away in the event that you develop: serious stomach pain, severe or nausea/vomiting that is persistent.

Stop taking this medication and tell your doctor right away if you develop these not likely but very serious negative effects: severe headache, vision changes, ringing ears, hearing loss, chest pain, yellowing eyes/skin, dark urine, severe diarrhoea, rectal blood.

A very severe allergic reaction to this drug is rare. However, seek immediate attention that is medical you notice any outward symptoms of a critical allergic effect, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your pharmacist or doctor.

Into the US -

Call your medical professional for medical advice about negative effects. You could report side effects to FDA at 1-800-FDA-1088 or at

In Canada - Phone your medical professional for medical advice about side effects. You'll report adverse effects to Health Canada at 1-866-234-2345.


Before taking isotretinoin, tell your physician or pharmacist if you are allergic to it; or to vitamin A-related drugs (other retinoids such as tretinoin); or if you have any other allergies. This product may contain ingredients that are inactivesuch as soybean, parabens), which can cause allergies or other dilemmas. Some individuals who are allergic to peanuts may also be allergic to soy. Speak to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, family or personal history of high blood fats (triglycerides), family or personal history of psychiatric disorders (including depression), liver disease, obesity, eating disorders (e.g., anorexia nervosa), alcohol abuse, pancreatitis, bone loss conditions (e.g., osteoporosis/osteomalacia, decreased bone density).

Do not donate bloodstream while you are taking isotretinoin and for at least 1 month after you stop taking it.

This medication might make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear clothing that is protective outside.

Isotretinoin can impact your vision night. Do not drive, use machinery, or do any activity that requires clear vision after dark until you are sure you can perform such activities safely.

You may not tolerate them as well as usual while using this medication if you wear contact lenses. Contact your medical practitioner to get more information.

Don't have cosmetic procedures to smooth your skin (e.g., waxing, laser, dermabrasion) during and for 6 months after isotretinoin therapy. Skin scarring may occur.

Avoid the use of alcohol while taking this medication because it may increase the risk of certain unwanted effects (e.g., pancreatitis).

Limited information suggests isotretinoin may cause some bone loss effects. Therefore, playing contact or repetitive impact sports (e.g., football, basketball, soccer, tennis) may result in bone problems, including an increased risk of broken bones. Limited information also suggests isotretinoin may stop normal growth in some children (epiphyseal dish closure). Check with your doctor for more details.

Care is recommended when using this drug in the elderly because they might be more sensitive to its impacts, particularly the effects on bones.

Care is recommended when using this drug in young ones because they may be more responsive to its impacts, specially back/joint/muscle pain.

This drug should not be utilized during maternity or by people who may become pregnant during treatment. You may be pregnant, inform your doctor right away if you become pregnant or think. See also Warning section.

Since this drug is absorbed through your skin and lungs and may harm an baby that is unborn women who're pregnant or who may become expecting should not handle this medication or breathe the dust from the capsules.

You must have two negative pregnancy tests before starting this medication. You must have a monthly pregnancy test during treatment with isotretinoin. If the test is good, you must stop taking this medication and consult your physician appropriate away.

It really is unknown if this medication passes into breast milk. However, similar drugs pass into breast milk. Breast-feeding while by using this drug is not advised. Consult your physician before breast-feeding.

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